A WSe2@poly(3,4-ethylenedioxythiophene) nanocomposite-based electrochemical sensor for simultaneous detection of dopamine and uric acid

Abstract

In the present work, a nanocomposite of two-dimensional WSe2nanosheets with poly-(3,4-ethylenedioxythiophene (WSe2@PEDOT) was prepared by facile hydrothermal method and characterized in terms of structural and morphological analyses. This nanocomposite was used to modify glassy carbon electrode for the construction of an electrochemical sensing platform for simultaneous determination of dopamine (DA) and uric acid (UA) in the presence of ascorbic acid (AA). It was found that the incorporation of PEDOT into WSe2nanosheets exhibited enhanced electrochemical behaviors and electro¬catalytic activity against DA and UA. Using differential pulse voltammetry (DPV) measurements, the WSe2@PEDOT modified electrode displayed wide linear detection ranges of 16 to 466 μM for DA and 20 to 582.5 μM for UA. The electrode also exhibited high selectivity against DA and UA in the presence of major interference of ascorbic acid and other interferent substances.