USLU, Hamit; ERDAĞ, Dinçer; ATİLA, Gözde; METİNER, Kemal; ÇELİK, Baran; KART, Asım; Esin KIRIK, Fatma; OZKAN, Oktay
Açıklama:
Caper plant belonging to the genus Capparis (family Capparaceae) is a plant used in traditional medicine to curevarious illnesses since ancient times. Studies have shown significant medicinalproperties of various Capparisspecies. This study was designed to examine invitro antifungal and antioxidant activity of methanolic extracts of Capparis ovata buds. It was determinedthat Capparis ovata inhibited the NOradical in a dose-dependent manner and exhibited reducing power activity.According to the standard pyrocatechol graph, 1 mg of Capparis ovata contains 19.64 µg of phenolic equivalent ofpyrocatechol. In vitro antifungalsusceptibilty testing of Capparisovata methanolic extract against eight different fungal strains were determined by broth macrodilutionmethod. According to MIC values of in vitro antifungal activity testing Capparis ovata has moderate antifungalactivity. In conclusion, Capparis ovata was found to have a significant antifungal andantioxidant potential. Hence, this plant could have the potential to be usedagainst fungal and oxidative stress related many disease conditions.