Açıklama:
Aspergillosis is a serious fungal diseases and it affected all of the animals including birds. The aim of this study is to present clinicopathological findings of severe aspergillosis and treatment of the diseases in a pigeon flock. In this study, 1-1.5 months old 17 pigeons from a flock of 85 presented with symptoms of respiratory distress, inappetence, torticollis, incoordination and 20% mortality were examined macroscopically and microscopically. At necropsy granulomatous lesions were observed mainly in air sacs and lungs. Microscopic examination of the squeeze preparation of the air sacs and lungs revealed the presence of typical conidiophores of an Aspergillus sp. Histopathologically, necrosis with heterophil leukocyte, lymphocyte, macrophage and giant cells were observed in the granulomatous lesions. Although severe nervous symptoms were observed there were no macroscopical lesions seen in brains and cerebellums, slight gliosis was diagnosed at histopathological examinations. Immunohistochemical examination of central nervous system for Newcastle Disease was negative. Fungal agents were demonstrated in lesions in lungs and air sacs with periodic acid Schiff (PAS) methods. After diagnosis the tiny house were ventilated remained pigeons without neurological but with general symptoms were treated with 10.3 mg/kg itraconazole and multivitamin complexes.