| dc.creator |
TUTUN, Soner |
|
| dc.creator |
KAYA, Muhammet Mükerrem |
|
| dc.creator |
USLUER, Melike Sultan |
|
| dc.creator |
TUTUN, Hidayet |
|
| dc.date |
2020-08-31T00:00:00Z |
|
| dc.date.accessioned |
2020-10-11T18:51:15Z |
|
| dc.date.available |
2020-10-11T18:51:15Z |
|
| dc.identifier |
https://dergipark.org.tr/tr/pub/maeuvfd/issue/55084/728975 |
|
| dc.identifier |
10.24880/maeuvfd.728975 |
|
| dc.identifier.uri |
https://hdl.handle.net/11672/3298 |
|
| dc.description |
St. Johns wort (Hypericum perforatum) is a medicinal plant that exhibits important biological activities exhibit important biological activities being antioxidant, anti-inflammatory, immunomodulatory and/or antitumour. The aim of this study was to investigate antiproliferative effect of H. perforatum oil purchased from a commercial vendor on mouse myeloma cells. The cells were treated with various concentration (10%, 5%, 2%, 1%, 0.5%, 0.25%, 0.2% and 0.1%) of dimethyl sulfoxide (DMSO) to determine the non-toxic concentration. The cells were treated with various concentrations (15.6-500 ppm) of the oil dissolved in DMSO to examine its antiproliferative activity. Non-toxic dose of DMSO was at the concentration of lower than 0.2%. No effect on the cell proliferation was observed in the applied concentration of the oil. In conclusion, the oil had no antiproliferative effect on Myeloma cells at these concentrations. |
|
| dc.format |
application/pdf |
|
| dc.language |
en |
|
| dc.publisher |
Mehmet Akif Ersoy University |
|
| dc.publisher |
Mehmet Akif Ersoy Üniversitesi |
|
| dc.relation |
https://dergipark.org.tr/tr/download/article-file/1265738 |
|
| dc.source |
Volume: 5, Issue: 2
79-82 |
en-US |
| dc.source |
2148-6239 |
|
| dc.source |
Veterinary Journal of Mehmet Akif Ersoy University |
|
| dc.subject |
Antiproliferative activity,Hypericum perforatum,Myeloma cells |
|
| dc.title |
Investigation of antiproliferative effects of Hypericum perforatum oil on myeloma cells |
en-US |
| dc.type |
info:eu-repo/semantics/article |
|