OpenAccess @MAKÜ

MAKÜ Open Access System

OpenAccess@MAKÜ is an academic, open-access repository. It aims to collect, preserve and make Burdur Mehmet Akif Ersoy University’s scientific output available online, without any or the least financial, legal or technical restrictions, in order to increase the impact and the visibility of the institution and its authors. It was established in 2011 to support the dissemination of knowledge produced by the University members to the wider community both locally and globally.

 

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Effects of Elizabethan Collar and Wound Protection Corset on Pain and Discomfort Levels in Cats Undergoing Ovariohysterectomy
(Veterinary Medicine and Science, 2025-01-19) Isil, Ayhan; Yanmaz, Latif Emrah
Objective: To compare the impacts of Elizabethan collar (EC) and wound protection corset (WPC) on pain and discomfort levels in cats following ovariohysterectomy. Study design: Prospective, randomized controlled clinical trial. Animals: Twenty-six healthy female cats. Methods: Animals were randomly assigned to two groups after midline celiotomy: One group wore an EC (n = 13), and the other wore a WPC (n = 13). Pain was evaluated using the Composite Measure Pain Scale-Feline (CMPS-F) and the Multidimensional Pain Scale (MCPS) at intervals of 6, 12, 24, 48, 72 and 96 h, with the requirement for rescue analgesia recorded. Discomfort was assessed through cortisol levels, behavioural observations and the frequency of misbehaviours. Results: No significant differences were observed between groups at all time intervals for CMPS-F and MCPS (p < 0.05). Rescue analgesic administration was similar between the groups, with 16 administrations in the WPC group and 17 in the EC group (p = 0.88). Cortisol levels also showed no significant difference between groups (WPC: 0.05 [0.05-0.3] vs. EC: 0.05 [0.05-0.8]; p = 0.09). Behavioural observations revealed significant differences in misbehaviours, with 10 out of 13 cats in the EC group attempting to remove their collars or exhibiting head shaking (p < 0.01), whereas no misbehaviours were noted in the WPC group. Conclusion: Both EC and WPC provided comparable pain management; however, the significant misbehaviours associated with EC use suggest increased discomfort level.
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A Study on SP-A Expression in Rat Testis during Postnatal Development
(Bratislava Medical Journal, 2025-04-17) Ozbek, Mehmet; Ata, Ayhan; Karaca, Harun; Oztop, Mustafa; Ergun, Emel; Kankavi, Orhan
Background Surfactant proteins A (SP-A) is integral components of the host defense system, known for their significant antimicrobial properties and diverse immunomodulatory functions, particularly within the lung alveolus. Although SP-A is expressed in the testis, its specific roles in testicular cells, especially in relation to spermatogenesis, remain inadequately characterized. Objective This study addresses the gap by investigating the localization and expression of SP-A in rat testis tissue at 5, 20, 50, and 70 days of postnatal development. Additionally, it examines the localization of SP-A in developing spermatid to spermatozoa within seminiferous tubules. Materials and Methods Wistar albino rats were divided into four groups (N = 6 per group) based on distinct postnatal developmental days (PNDs): 5, 20, 50, and 70. The expression level of SP-A was estimated using Western blotting, and immunohistochemistry analysis was conducted. Results At PND 50, SP-A immunoreactivity was present in elongating spermatids (steps 9–15) and increased at PND 70. Notably, SP-A signals in elongated spermatids (steps 16–19) at PND 50 intensified and peaked at step 16 in early-stage I-II at PND 70 and began to decrease in steps 17–19 in stages IV-XIV at PND 70. Western blot analysis of testis tissue extracts also confirmed the gradual increase in SP-A expression corresponding to postnatal development days. Conclusion These findings suggest that SP-A may serve similar functions in rat testicular tissue as in lung alveoli, including roles in innate immunity, host defense, modulation of the immune response, regulation of inflammation, and protection against infections also may play a role in spermatogenesis and steroidogenesis.
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The Relationship of Depth of Anaesthesia With Blink Reflex in Cats
(Veterinary Medicine and Science, 2025-04-30) Sirin, Ozlem Sengoz; Elvan, Ayse Nihan
Background: The blink reflex is a neurological response characterised by eyelid movements and can provide important data on the state of anaesthesia. Sevoflurane is a commonly used inhalation anaesthetic agent in cats and evaluation of eye reflexes under this agent may help to better understand the depth of anaesthesia. Objectives: The aim of this study was to evaluate the relationship between the blink reflex and the depth of anaesthesia in cats and to evaluate the parameters that can be obtained from the blink reflex in addition to its effect in determining the depth of anaesthesia. Methods: All cats were premedicated with midazolam 0.1 mg kg−1 and butorphanol 0.4 mg kg−1. Propofol at a dose of 4 mg kg−1 was administered for the induction of anaesthesia. Following this, anaesthesia was maintained with sevoflurane. Anaesthesia was maintained at a minimum alveolar concentration (MAC) value of 2.9, which is the end-tidal MAC value that provides deep anaesthesia for cats. Following the end of the operation, electrical stimulation was given to the supraorbital nerve for each 0.1 for each decreasingMAC value starting from the end-tidalMAC value of 2.9, and blink parameters were recorded from the orbicularis oculi muscle. In this study, the mean latency, amplitude and duration values in sevoflurane anaesthesia in cats were determined. Results: In cats, only two blink responses, R1 and R2, were found in all MAC values. At the same time, a very strong positive correlation was found between R1 latency and MAC, and a moderate negative correlation was found between R2 latency and MAC. There was a very strong negative correlation between R1 amplitude and MAC and a moderate positive correlation between R2 amplitude andMAC. Therewas amoderate negative correlation between R1 duration andMAC and a weak negative correlation between R2 duration and MAC. When the relationship between anaesthesia stages and MAC was compared, R1 amplitude and R2 amplitude were found to be significant only between stage II and awake stage. In all other stages, R1 latency, R2 latency, R1 amplitude and R2 amplitude were not significant. All cats woke up with an average MAC value of 0.43 ± 0.20. Conclusions: In this study, mean latency, amplitude and duration values in cats under sevoflurane anaesthesia were determined. It was demonstrated that it was possible to elicit blink parameters in cats under sevoflurane anaesthesia with a short stimulus sequence to the supraorbital nerve. Only two blink responses, R1 and R2, were elicited at all MAC values.
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Is There A Causal Relationship Between Financial Performance And Premium Production? Evidence From Turkish Insurance Industry
(Journal Of Mehmet Akif Ersoy University Economics And Administrative Sciences Faculty, 2023-09-02) Işık, Özcan; Shabir, Mohsin; Belke, Murat
This study aims at determining the causal link between financial performance and premium production of non-life insurance companies. The relation between the financial performance and premium production is explored employing data from the 2011-2019 period for eight Turkish non-life insurance companies. In the first stage of the analysis, a hybrid model including LOPCOW, SWARA II, and MARCOS methods is proposed to determine companies’ financial performance values. In this stage, a novel integrated weighting method for calculating criterion weights is applied based on objective information and judgements of decision-makers. In the second stage, the association between financial performance and premium production is investigated by correlation analysis. In the last stage, the causality linkage between the two variables is estimated using a panel causality test developed by Dumitrescu and Hurlin (2012). According to the results obtained from the panel causality test, the bidirectional causality relation exists between financial performance and premium production. Besides, the individual panel causality results reveal that bidirectional causality is valid for only Allianz and Anadolu insurance companies, which had an average share of over 35% in total non-life premium production during the analysis period. The paper provides fresh evidence on the association between the financial performance and premium production, particularly from the Turkish context
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A Scale Development Study To Determıne Psychosocıal Evaluatıons For Seafarers
(Journal Of Mehmet Akif Ersoy University Economics And Administrative Sciences Faculty, 2023-09-02) Öksüz, Sena; Yanardağ, Umut
Seafarers who spend long periods at sea and therefore have little contact with life on land face various difficulties because of their strenuous working conditions. While identifying those challenges and carrying out psychosocial interventions has the potential to increase the psychosocial well-being of seafarers, there is no scale to determine the psychosocial risks that seafarers contend with in the course of their work. This study was conducted with the aim of identifying the elements of the psychosocial risks they face so such a scale can be developed. A preliminary form was prepared for that purpose. Once the validity reliability rate of the form was determined on the basis of feedback, it was submitted to 735 members of the Turkish Seafarers ' Union residing in Istanbul and the resultant data was analyzed with SPSS and AMOS. As a result of the exploratory factor analysis, 3 factors named “Psychological/Spiritual Problems”, “Problems Related to Family and Environment” and “Problems Related to Work Environment” and 26 items were determined. It was determined that the total variance explained was 60.02%. In the confirmatory factor analysis performed, the structure consisting of 26 items and 3 sub-dimensions provided good fit values. As a result, it was concluded that a 3-factor Psychosocial Evaluation Scale for Seafarers consisting of 26 items is a valid and reliable scale.